Bio-Monitoring Instruments, Chemicals and Media.
Clarigard® Filters
Clarigard® filters’ 99.99% retention characteristic makes them ideal for the protection of critical downstream process steps such as membrane filters or chromatography columns. The graded-density depth structure of Clarigard® filter media provides maximum filtration capacity, and the polypropylene construction offers low extractable levels and broad chemical compatibility.
Clarisolve® Depth Filters for Primary Clarification of Pretreated Feed Streams
The Clarisolve® depth filter is the first primary clarification offering with a gradient density structure specifically designed to the particle size distributions of pretreated feed streams.
Millistak+® Pod Disposable Depth Filter System
Millistak+ depth filter media is offered in a scalable, disposable format, the Pod Filter System. Accommodating applications from lab to pilot to process scale, the Pod format offers greater flexibility because of its unique modular design.
EMD Millipore All-Glass Filter Holder, 47mm
Vacuum filter aqueous, organic, or corrosive liquids for particulate or biological contamination analysis. EMD Millipore All-Glass Filter Holder, 47mm is a complete assembly constructed entirely of borosilicate glass with an aluminum clamp. Recommended for HPLC solvent filtration.
Exact-Air™ II Automatic, Water-based Integrity Testing Option
Regulatory agencies require that bioprocessing equipment with critical sterilizing-grade vent filters, such as blowfill-seal systems, autoclaves, freeze dryers, WFI vessels, production tanks, washing machines and fermenters, must be periodically integrity tested. In fact, many biopharmaceutical manufacturers are increasingly testing filters before and after use. This production step requires a fast, reliable and validatable test method that is widely accepted by the industry and regulatory agencies. Unfortunately, many of the gas-based test methods used are highly sensitive to the effects of temperature. Additionally, the access to the vent filters is often difficult, due to their position in technical areas or on the dome of large tanks.
Mobius® Handling and Storage Systems
Mobius Handling and Storage Systems are key components in delivering efficient, ergonomic and scalable process solutions to your production lab. Consisting of a series of polyethylene drums, stainless steel bins and single-use assemblies, Mobius Handling and Storage Systems are designed to reduce operator error and improve process efficiency. With a full spectrum of systems to choose from, you get greater flexibility, mobility and support for your single-use technologies.
Millidisk Sanitary HousingsTM
Designed for Sterilization of High Value – Low Volume Biopharmaceutical Products. Uses the Unique Stacked Disc Concept of Millidisk Cartridges.
Pellicon® XL 50 Cassette and Labscale TFF System
Easy-to-use, high-performance, tangential flow filtration cassette and system for process development work at volumes from 50 to 1000 mL.
Steritest™ Symbio Pumps
Designed to integrate perfectly into all testing environments, streamlining your workflow, maximizing safety and convenience.
AerventTM-50 Cartridge Filters
Cost-effective sterile gas filtration is assured by maximizing the useful service life of a hydrophobic filter device while minimizing associated risk of service-related filter integrity failures. Fractional sanitary flange connections eliminate the need for adapters, clamps and tubing and ensure that air flow will not be impeded by bent or pinched tubing.
Sterilizing-grade Aervent® Filters
The 0.2 µm hydrophobic Aervent polytetrafluoroethylene (PTFE) membrane provides sterility assurance high flow rates and throughput. The Aervent membrane contributes to clean processes due its non-fiber releasing properties.
Sterilizing-grade Durapore® 0.1 µm and 0.22 µm Hydrophilic Filters
Durapore sterilizing-grade 0.1 µm and 0.22 µm hydrophilic polyvinylidene fluoride (PVDF) membranes are low protein binding and provide sterility assurance, high flow rates, and throughputs. The Durapore membrane contributes to clean processes due to low extractables, broad chemical compatibility, and its non-fiber releasing properties.
Durapore® 0.45μm Hydrophilic Filters
Hydrophilic 0.45 μm Durapore polyvinylidene fluoride (PVDF) membrane provides low protein binding, high flow rates, and high throughputs. Durapore 0.45 μm membrane contributes to clean processes due to low extractables, broad chemical compatibility, and its non-fiber releasing properties. Durapore 0.45 μm hydrophilic filters remove particles and microorganisms from aqueous liquid streams. These filters are ideally suited for large volume parenteral or ophthalmics manufacturing, where prefiltration is either unnecessary or already present at an earlier point in the process, or where protein binding must be minimized.
Hydrophilic Multilayer Durapore® 0.45/0.22µm Filters
The combination of hydrophilic low protein binding 0.45 μm Durapore® polyvinylidene fluoride (PVDF) membrane and sterilizing-grade 0.22 μm Durapore membrane in a single cartridge or capsule is the superior choice for clean and sterile processes due to low extractables, broad chemical compatibility, and its non-fiber releasing properties. Sterilizing-grade, Hydrophilic Multilayer Durapore 0.45/0.22 μm filters maximize process efficiency by providing high product recovery and extended throughput with low pressure drops. Hydrophilic Multilayer Durapore 0.45/0.22 μm filters are recommended for a wide range of pharmaceutical and biological liquid applications, including the filtration of therapeutics, vaccines, antibiotics, blood fractionations, bulk pharmaceutical and other downstream biotechnology processing solutions where protein binding must be minimized. Hydrophilic Multilayer Durapore filters are ideally suited to applications requiring high sterility assurance, high product purity, and high product yield.
Multiple Integrity Testing System For Aervent 50 – Manifold
Aervent hydrophobic filter contains a 50 mm Aervent PTFE bidirectional membrane supported by a polypropylene casing. This Sterile Grade filter is designed for critical small-scale gas line and air venting applications. In situations where the particles are hard, the sizing of the filtration system is done according to the flow rate. To ensure consistent sterilizing grade performance, each unit is integrity tested prior to packaging with an integrity test correlated to Brevundimonas dimunata retention using the ASTM F838-05 Challenge Methodology.
AceLinerTM Plus Cartridge Housings
The new AceLiner Plus – all 316L stainless steel cartridge filter housings are designed primarily for sterile liquid filtration in the biopharmaceutical industry. The sanitary design, including all TM connections and accessories of AceLiner Plus ensure that clean-in-place (CIP), steam-in-place (SIP), and filtration operations can be efficiently and effectively completed. The design and cGMP detailing that goes into the manufacture of these housings is the result of more than 50 years of Millipore expertise and leadership in filtration. Attention is given to each and every component that goes into the housing. From the certification of the 316L stainless steel by The American Iron and Steel Institute (AISI), to the fine electro polishing processes controlling Ra, the special (GTAW) process for high precision welding, the clean valve connections, TC clamps, and sealing material used.
Optiseal® Cartridge Filters with Aervent® Membrane
Optiseal® filters with Aervent® membrane are 0.2 μm hydrophobic cartridges. They are designed for sterilizing applications, removing particles and microorganisms from gases and solvents. They are made with PTFE membrane and polypropylene components for broad application compatibility.
Lifegard™ Filters
Lifegard glass microfiber medium was designed for removal of deformable and non-deformable particles and microorganisms from liquids. Versatile depth-type products retain contaminants within the matrix of glass microfiber medium. The Lifegard media is used to achieve exceptional retention efficiency. Because of its high holding capacity, adsorptive removal properties, and excellent wet strength, it is very well-suited for the clarification and prefiltration of serum, plasma proteins, gene therapy, and other viscous biologicals.